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Mother Machine chip

2024-01-31

Microfluidic mother machine chip is an advanced biochip technology that integrates microfluidics and cell biology, aiming to simulate and study various stages of mother cells in the cell cycle and related molecular and biological processes. This technology utilizes microstructures such as microchannels, microreactors, and microvalves for highly precise manipulation and observation of mother cells at the microscopic scale. The following is a detailed overview of the mother machine chip, covering its principles, applications, advantages, and potential impact on cell biology and medical research.

Plant microfluidic chips

2024-01-31

Plant microfluidic chips are increasingly important tools in the field of plant science, with applications spanning plant growth, plant physiology, and plant stress responses. These chips leverage microfluidic technology to finely control and analyze plants through microchannels and microreactors, providing a novel approach to studying plant growth and development, metabolic processes, and plant responses to environmental changes. The following is an overview of plant microfluidic chips, including their principles, applications, advantages, and potential contributions to plant science research.

Lung chip/Lung on a chip

2024-01-25

Microfluidic Lung Organ Chip is a micro experimental platform designed and fabricated based on microfluidics technology to simulate the structure and function of the lungs. It is a micro-organ composed of a series of micro-channels, chambers and cell culture membranes, which can simulate physiological and pathological processes such as respiratory movements, exchange of oxygen and carbon dioxide, and immune responses in the lungs.

Engineered Heart Tissue Chips

2024-01-19

Heart disease has consistently been a major global health concern, and the research and screening of drugs are crucial for treating these conditions. In recent years, an innovative technology called Engineered Heart Tissue Chips (organ on a chip, microfluidic chips) has garnered widespread attention. This technology utilizes Engineered Heart Tissue (EHT) to create a unique drug screening platform, simulating the three-dimensional structure and mechanical responsiveness of real heart tissue, providing researchers with a more realistic and controllable experimental environment. This article will delve into the key features, advantages, and potential applications of Engineered Heart Tissue Chips in the development of cardiac tissue and the pharmaceutical research field.

Microfluidic PEEK Chips/Cell Culture Chips

2023-10-30

Many in vitro methods have long been used for high-throughput drug screening or toxicology testing. However, most of the currently available systems are only partial approximations of human biology and therefore have limited predictive power. Indeed, these systems are either based on human cell cultures, which are unable to capture the complexity of cell behavior in a three-dimensional (3D) environment, or on animal tissue fragments, which are 3D in nature but only partially biologically similar to human tissues, and are unable to account for interactions with other organs. To overcome these limitations, a new generation of bioreactors is being developed to generate multiple human cell-based tissue analogs in the same fluidic system to better reproduce the complexity and interconnections of human physiology. These efforts are aimed at creating multi-tissue organ systems (cardiovascular, gastrointestinal, musculoskeletal, etc.) and ultimately connecting them into an interconnected human-on-a-chip device that is capable of realistically recreating the complexity of the human body's response to disease and potential drug treatments.

organoid chip

2023-10-23

Dual Flow Channel Design Organoid Chip An advanced organoid chip technology inspired by the concept of organoid chips, it consists of two independent channels that support 2D and 3D cell cultures to mimic physiological environments, especially in the study of the effect of fluid shear stress on gene expression in blood vessels.