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Top Asahi provides various microfluidic chips, microfluidic chip processing equipment and microfluidic commonly used consumables, and we also provide professional microfluidic chip customization services.
Top Asahi provides various microfluidic chips, microfluidic chip processing equipment and microfluidic commonly used consumables, and we also provide professional microfluidic chip customization services.
In today's biomedical research field, organ chip/cell culture chip/organoid chip technology is pushing the boundaries of science at an astonishing speed. In order to realize more realistic and efficient biological experiments, organ chip/cell culture chip/organoid chip processing equipment has become an indispensable key element.
Many in vitro methods have long been used for high-throughput drug screening or toxicology testing. However, most of the currently available systems are only partial approximations of human biology and therefore have limited predictive power. Indeed, these systems are either based on human cell cultures, which are unable to capture the complexity of cell behavior in a three-dimensional (3D) environment, or on animal tissue fragments, which are 3D in nature but only partially biologically similar to human tissues, and are unable to account for interactions with other organs. To overcome these limitations, a new generation of bioreactors is being developed to generate multiple human cell-based tissue analogs in the same fluidic system to better reproduce the complexity and interconnections of human physiology. These efforts are aimed at creating multi-tissue organ systems (cardiovascular, gastrointestinal, musculoskeletal, etc.) and ultimately connecting them into an interconnected human-on-a-chip device that is capable of realistically recreating the complexity of the human body's response to disease and potential drug treatments.
Dual Flow Channel Design Organoid Chip An advanced organoid chip technology inspired by the concept of organoid chips, it consists of two independent channels that support 2D and 3D cell cultures to mimic physiological environments, especially in the study of the effect of fluid shear stress on gene expression in blood vessels.
Sperm sorting chips represent an advanced technological tool designed specifically for reproductive therapy. Its core advantages include efficient selection of ideal sperm without the need for cumbersome sample preparation, as well as a standardized and streamlined operational process. This innovative chip combines optimized channel dimensions and incubation time to maximize sorting efficiency. Through this technology, high-quality sperm with attributes such as high motility, normal morphology, low ROS (Reactive Oxygen Species), and low DNA fragmentation can be quickly and accurately selected. The sperm sorting chip not only significantly reduces sample preparation time but also mitigates the impact of traditional centrifugation methods on semen quality, providing embryologists with an efficient and straightforward method to select the highest quality sperm, thereby enhancing the success rate of reproductive therapy.
Cell migration, which refers to the movement of a cell after it receives a migration signal or senses a concentration gradient of some substance. During movement, the cell repeats the cyclic process of extending synapses/pseudopods anteriorly and then pulling on the posterior cytosol. The cytoskeleton and its binding proteins, as well as the intercellular matrix, are the material basis for this process, which is finely regulated by a variety of other substances.
Cell culture microarrays, also known as cell chips or microfluidic cell culture chips, are an innovative tool in the field of cell biology that is changing the landscape of cell research and medical applications in unprecedented ways.
The Nucleic Acid Mass Spectrometry Chip (SpectroCHIP Array) is an advanced biochip technology primarily applied in genomics research and DNA sequencing. This chip features highly integrated functions, enabling simultaneous gene sequencing of multiple DNA samples on a single chip. Utilizing high-throughput optical detection technology allows efficient and precise analysis of DNA fragments. Its design addresses the need for high automation, enabling users to acquire large-scale genetic data more rapidly and reliably. This technology finds extensive applications in disease research, personalized medicine, and bioinformatics, playing a crucial role in advancing genomics research and DNA sequencing. The innovative design of the Nucleic Acid Mass Spectrometry Chip makes it a highly acclaimed technology in the current field of gene sequencing.
A 3D cell culture chip is a biotechnology tool used to simulate and study three-dimensional cell growth environments in the laboratory. Traditional cell culture is usually performed in a 2D petri dish, but this method cannot accurately simulate the 3D growth of cells in the human body.
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